In addition to NX-OS the Nexus 9300 also supports the ACI image (controller based SDN alterative) VXLAN configuration is robust in NX-OS than IOS XE if you have a need for it. Things like vPC and support for FCoE are NX-OS exclusive features for example (note FCoE and MACSEC are only available using the more expensive FX line instead of EX). IOS XE and NX-OS support sine different features. That said if you're looking at creating a data center environment that will leverage things like VXLAN or automation then the Nexus line will be the most common, most supported, and most widely adopted solution. If you're not experienced with NX-OS and are more comfortable sticking with IOS XE the Catalyst 9000 series can be a safe choice for small server switch needs. Nexus models used to have considerable performance advantages over the Catalyst but the Catalyst 9000 series has closed the gap considerably.
The Catalyst line is focused on campus networking (core access and distribution). The Nexus line is dedicated to data center needs and that is where the development focus is.
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